i

Organic Chemistry

Characteristics of Diastereoisomers

Characteristics of Diastereoisomers

  • Diastereoisomers show different physical and chemical properties. They have different melting point points, densities, solubility, etc.
  •  Diastereoisomers are easily separated by fractional crystallization, fractional distillation, chromatography, etc.
  • Diastereoisomers encounters the case of geometrical isomers.

  1. Conformational Stereoisomerism

Free rotation about the C-C bond axis results in a different arrangement of atoms in space called conformers. This phenomenon is called conformation isomerism. The various bond length and bond angles remain the same in conformers. Infinite no. of conformers of a molecule exist, two of them are defined as eclipsed and staggered.

Note: For conformation, there should be a sigma bond present in the molecule.